Animal-Free Inhalation Testing? Talk About a Breath of Fresh Air

Written by PETA | January 8, 2018

Rats and other animals used in toxicity testing can breathe easier, thanks to a recent report published in the journal Toxicology in Vitro. In a major collaborative effort with government and industry officials, PETA scientists spearheaded the publication detailing ways to replace animals in inhalation tests.

LEFT: Rats squeezed into inhalation tubes.

Currently, animals are squeezed into narrow tubes in which they are immobilized and forced to inhale toxic substances for hours on end before being killed and their bodies dissected.

The PETA International Science Consortium Ltd. co-authored the comprehensive report with the U.S. Environmental Protection Agency, The Dow Chemical Company, Syngenta, British American Tobacco, the University of Pennsylvania, and Cardiff University, among others.

This collaborative work is critical to ensure that any new approaches developed will have buy-in from the industries that conduct the research and the regulatory agencies that require that testing be conducted.

The non-animal approaches include computer modeling and the use of 3-D tissues that can be exposed to test substances in ways that mimic realistic human exposure. To help researchers conduct non-animal inhalation testing, the PETA International Science Consortium also provided inhalation testing devices that do not use animals—over $400,000 worth—to four pioneering laboratories around the world.

The PETA International Science Consortium is thrilled to be working with forward-thinking scientists in industry and government who are ushering in new, more human-relevant toxicity testing methods that both protect human health and spare animals’ lives.

You Can Help, Too!

Reliable non-animal testing methods are available, and many more are being developed. Using non-animal tests will produce safer and more effective drugs and reduce the cost of bringing drugs to market. Click the button below to ask the FDA to accept superior non-animal methods in place of archaic and unreliable animal tests: